Cell Dynamics W8

Cell Dynamics’s W8 Physical Cytometer is the only fully automated instrument for the physical characterization of 3D sphere-like biological samples.
It covers the range from 50 μm sized small clusters up to larger spheroids or organoids with 500 μm in diameter. The combination of ground-breaking flow-based technology with bright-field image-based analysis provides the user with an entire data set of sample’s mass density, weight and size, in just few minutes.
And even more important, physical-based sorting of target sub-populations can be operated based on pre-selected ranges of diameter or mass density.

Cell Dynamics​

Cell Dynamics was established in Bologna, Italy with the focus on development of microfluidic devices for the analysis of 3D cell culture, especially 3D spheroids and organoids. Their W8 Physical Cytometer is so far the only fully automated instrument to analyze physical characterization out of your 3D sphere like biological samples.

W8 Physical Cytometer can work with any sphere like biological samples that ranges from 50 μm to 500 μm spheroids or organoids in diameter. With its flow-based technology and bright field image-based analysis software, W8 is able to deliver physical characterization out of your samples such as mass density, weight and size in just a few minutes. Another benefit of this system is that it can sort your samples based on either ranges of mass density or diameter without any sheer stress as it calculates the flow rate for gentle sorting. Moreover, with this label free technology, the researchers are able to preserve sterility and viability of their samples after W8 Physical Cytometer is done with analyzing the samples. This is the perfect solution for the researchers who are looking for growth monitoring, standardization, uniformity in their 3D sphere like biological samples. ​

Cell Dynamics - Applications

Here are some W8 Physical Cytometer applications​

Biophysical heterogeneity

Quality control​

Viability correlation

Cell killing activity​

Cell counting correlation​

Cell permeation rate

Cell mode of action based on samples’ biophysical properties​

Biophysical determination of in vitro drug efficacy

Determination of tumor-induced morphological changes