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Life Science Equipment. Label-free Live Cell Imaging

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Welcome to
NEXUS SCIENTIFIC

Life Science Equipment. Label-free Live Cell Imaging

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ABOUT US

Who We Are

Nexus Scientific is a Life Science Service business providing International Trade, Business Development and Distribution within the Analytical Science, Biopharmaceutical and Diagnostic industries.

Nanolive 3D Cell Explorers

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A stem cell differentiation story

In this video, we have created a timeline showcasing the temporal responses of human mesenchymal stem cells to neurogenic differentiation media. All images were taken using Nanolive’s CX-A (nanolive.ch/products/3d-microscopes/cx-a/):

In the first video, refractive index images were captured once every 7 mins for 12 h, using the 3×3 gridscan mode (a field of view of 275×275 µm).

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Stem cell differentiating into neuronal cells

In this video, we observe the morphological changes umbilical cord matrix human mesenchymal stem cells undergo upon exposure to neurogenic differentiation media

Images were captured once every 4.5 mins for 22 h using the 5×5 gridscan mode (a field of view of 450×450 μm) on Nanolive’s CX-A (nanolive.ch/products/3d-microscopes/fluo/).

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Label-free Live Cell Imaging: Diving into the immune system - APC T-Cells interaction/activation experiment

In this video we see the T-Cell activation totally marker-free. Pre-stimulated antigen presenting cells (APCs*: dendritic cells and macrophages) are cultured with freshly isolated “naïve T-cells”, the OT-I mice T-cells in order to teach them to recognize and kill the tumor cells.
* APCs are special cells that present the antigens on their surface so that other immune cells can “see” and detect it.

Technology:
3D Cell Explorer microscope from Nanolive, Switzerland.

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Labelfree microscopy: Long Term Live Imaging of Mouse Pre-adipocytes (48hrs)

Live imaging of mouse pre-adipocytes for 48 hours. 1 image per minute. This is label-free yet you can see amazing biology unfolding under your eyes! This is unique material as never seen before.

Technology: 3D Cell Explorer microscope from Nanolive, Switzerland.

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Multi-well, time-lapse imaging of live pre-adipocytes perturbed by different drugs | Nanolive imaging

In this video, we observe the response of pre-adipocyte cells grown in 96 well plates to Tamoxifen, Raptinal, and Shikonin. Drugs were applied at various concentrations, with or without the fluorescent probe MitoTracker added. Unperturbed cells were included as a negative control.

3D CELL EXPLORER

A high‐speed, high‐resolution and non‐invasive microscope that can look deep inside biological systems and record 3D images of cells in just seconds.

3D CELL EXPLORER-FLUO

A powerful platform to combine the benefits of non-invasive 3D tomography with a well-established and recognized multi-channel epifluorescence allowing to extend the field of research.

CX-A

A unique, fully automated walk-away solution for long-term live cell imaging and drug discovery across a multi-well format to screen dozens of samples at once.